ENT Updates
Clinical Research

A great mimicker of mastoiditis: Multisystem Langerhans’ cell histiocytosis

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Department of ORL-HNS, Queen Elizabeth Hospital, Sabah, Malaysia

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Department of Pathology, School of Medical Sciences, University Sains Malaysia, Health Campus, Kelantan, Malaysia

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Department of ORL-HNS, University Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia

ENT Updates 2020; 10: 296-299
DOI: 10.32448/entupdates.673014
Read: 1006 Downloads: 541 Published: 28 January 2021

Langerhans’ cell histiocytosis (LCH) is a rare group of diseases characterized by abnormal clonal proliferation of Langerhans cells in one or more systems. LCH can occur in any system. We report a case of bilateral otologic LCH that presented as a case of mastoiditis. Despite multiple courses of antibiotics, there was no improvement. Subsequent excision biopsy of a postauricular mass confirmed the diagnosis of LCH. The patient responded well to chemotherapy

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